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Proceedings Paper

Hyperspectral imaging utilizing LCTF and DLP technology for surgical and clinical applications
Author(s): Karel J. Zuzak; Robert P. Francis; Eleanor F. Wehner; Jack Smith; Maritoni Litorja; David W. Allen; Chad Tracy; Jeffrey Cadeddu; Edward Livingston
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Paper Abstract

Two different, already characterized, hyperspectral imaging systems created for visualizing the spatial distribution of tissue oxygenation non-invasively for in vivo clinical use are described. Individual components of both liquid crystal tunable filter (LCTF) and digital light processing (DLP) systems were characterized, calibrated, and found to be well within manufacturer specifications. Coupling LCTF with charge coupled device (CCD) technology and acquiring images at multiple, contiguous wavelengths and at narrow bandwidths are formatted into a hyperspectral data cube consisting of one spectral and two spatial dimensions. DLP® technology has the novel ability to conform light to any desired spectral illumination scheme. Subsequently the collected multispectral data are processed into chemically relevant images that are color encoded at each pixel detector for the relative percentage of oxyhemoglobin. Using spectral illumination methods unique to the DLP hyperspectral imager results in producing chemically relevant images at near video rate; 4 frames per second. As an example, both systems are used to collect spectral data from a 27.22 kg porcine kidney whose renal artery has been occluded for 60 minutes. Both systems return nearly identical spectra collected from the surface of the kidney, with a root mean square deviation between the two spectra of 0.02.

Paper Details

Date Published: 23 February 2009
PDF: 9 pages
Proc. SPIE 7170, Design and Quality for Biomedical Technologies II, 71700C (23 February 2009); doi: 10.1117/12.816279
Show Author Affiliations
Karel J. Zuzak, The Univ. of Texas at Arlington (United States)
Robert P. Francis, The Univ. of Texas at Arlington (United States)
Eleanor F. Wehner, The Univ. of Texas at Arlington (United States)
Jack Smith, Texas Instruments (United States)
Maritoni Litorja, National Institute of Standards and Technology (United States)
David W. Allen, National Institute of Standards and Technology (United States)
Chad Tracy, University of Texas Southwestern Medical Ctr. (United States)
Jeffrey Cadeddu, University of Texas Southwestern Medical Ctr. (United States)
Edward Livingston, University of Texas Southwestern Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 7170:
Design and Quality for Biomedical Technologies II
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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