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Proceedings Paper

Can normal lymph node architecture be characterised by optical coherence tomography?
Author(s): R. A. McLaughlin; L. Scolaro; B. R. Klyen; S. Hamza; P. Robbins; C. Saunders; D. D. Sampson
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Paper Abstract

Assessment of lymph node involvement is a key prognostic marker in early breast cancer. This paper demonstrates the ability of optical coherence tomography (OCT) to characterise the micro-architecture of healthy, non-cancerous lymph nodes. OCT is shown to differentiate stroma, cortex and adipose tissue. Characteristic patterns are also identified for germinal centres and blood vessels within the node. Results are correlated against a histopathological gold standard.

Paper Details

Date Published: 30 December 2008
PDF: 3 pages
Proc. SPIE 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, 71390K (30 December 2008); doi: 10.1117/12.815182
Show Author Affiliations
R. A. McLaughlin, Univ. of Western Australia (Australia)
L. Scolaro, Univ. of Western Australia (Australia)
B. R. Klyen, Univ. of Western Australia (Australia)
S. Hamza, Sir Charles Gairdner Hospital (Australia)
P. Robbins, PathWest QEII Medical Ctr. (Australia)
C. Saunders, Sir Charles Gairdner Hospital (Australia)
Univ. of Western Australia (Australia)
D. D. Sampson, Univ. of Western Australia (Australia)


Published in SPIE Proceedings Vol. 7139:
1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics
Adrian Podoleanu, Editor(s)

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