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Proceedings Paper

A cardiac phantom study on quantitative correction of coronary calcium score on multi-detector, dual source, and electron beam tomography for velocity, calcification density, and acquisition time
Author(s): Marcel J. W. Greuter; Jaap M. Groen; Lieuwe J. Nicolai; Hildebrand Dijkstra; Matthijs Oudkerk
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Paper Abstract

Objective: To quantify the influence of velocity, calcification density and acquisition time on coronary calcium determination using multi-detector CT, dual-source CT and EBT. Materials and Methods: Artificial arteries with four calcifications of increasing density were attached to a robotic arm to which a linear movement was applied between 0 and 120 mm/s (step 10 mm/s). The phantom was scanned five times on 64-slice MDCT, DSCT and EBT using a standard acquisition protocol and the average Agatston score was determined. Results: Increasing motion artifacts were observed at increasing velocities on all scanners, with increasing severity from EBT to DSCT to 64-slice MDCT. The Agatston score showed a linear dependency on velocity from which a correction factor was derived. This correction factor showed a linear dependency on calcification density (0.92≤R2≤0.95). The slope and offset of this correction factor also showed a linear dependency on acquisition time (0.84≤R2≤0.86). Conclusion: The Agatston score is highly dependent on the average density of individual calcifications. The dependency of the Agatston score on velocity shows a linear behaviour on calcification density. A quantitative method could be derived which corrects the measured calcium score for the influence of velocity, calcification density and acquisition time.

Paper Details

Date Published: 13 March 2009
PDF: 6 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 725835 (13 March 2009); doi: 10.1117/12.813617
Show Author Affiliations
Marcel J. W. Greuter, Univ. Medical Ctr. Groningen (Netherlands)
Jaap M. Groen, Univ. Medical Ctr. Groningen (Netherlands)
Lieuwe J. Nicolai, Univ. Medical Ctr. Groningen (Netherlands)
Hildebrand Dijkstra, Univ. Medical Ctr. Groningen (Netherlands)
Matthijs Oudkerk, Univ. Medical Ctr. Groningen (Netherlands)


Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)

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