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Proceedings Paper

System architecture and information model for integrated access to distributed biomedical information
Author(s): Dongkyu Kim; Adil Alaoui; Betty Levine; Leonidas Leondaridis; Peter Shields; Steve Byers; Kevin Cleary
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Paper Abstract

The current trend towards systems medicine will rely heavily on computational and bioinformatics capabilities to collect, integrate, and analyze massive amounts of data from disparate sources. The objective is to use this information to make medical decisions that improve patient care. At Georgetown University Medical Center, we are developing an informatics capability to integrate several research and clinical databases. Our long term goal is to provide researchers at Georgetown's Lombardi Comprehensive Cancer Center better access to aggregated molecular and clinical information facilitating the investigation of new hypotheses that impact patient care. We also recognize the need for data mining tools and intelligent agents to help researchers in these efforts. This paper describes our initial work to create a flexible platform for researchers and physicians that provides access to information sources including clinical records, medical images, genomic, epigenomic, proteomic and metabolomic data. This paper describes the data sources selected for this pilot project and possible approaches to integrating these databases. We present the different database integration models that we considered. We conclude by outlining the proposed Information Model for the project.

Paper Details

Date Published: 13 March 2009
PDF: 9 pages
Proc. SPIE 7264, Medical Imaging 2009: Advanced PACS-based Imaging Informatics and Therapeutic Applications, 72640G (13 March 2009); doi: 10.1117/12.813397
Show Author Affiliations
Dongkyu Kim, Imaging Science and Information Systems Ctr., Georgetown Univ. (United States)
Adil Alaoui, Imaging Science and Information Systems Ctr., Georgetown Univ. (United States)
Betty Levine, Imaging Science and Information Systems Ctr., Georgetown Univ. (United States)
Leonidas Leondaridis, Lombardi Comprehensive Cancer Ctr. at Georgetown Univ. (United States)
Peter Shields, Lombardi Comprehensive Cancer Ctr. at Georgetown Univ. (United States)
Steve Byers, Lombardi Comprehensive Cancer Ctr. at Georgetown Univ. (United States)
Kevin Cleary, Imaging Science and Information Systems Ctr., Georgetown Univ. (United States)


Published in SPIE Proceedings Vol. 7264:
Medical Imaging 2009: Advanced PACS-based Imaging Informatics and Therapeutic Applications
Khan M. Siddiqui; Brent J. Liu, Editor(s)

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