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Proceedings Paper

Systolic and diastolic assessment by 3D-ASM segmentation of gated-SPECT Studies: a comparison with MRI
Author(s): C. Tobon-Gomez; B. H Bijnens; M. Huguet; F. Sukno; G. Moragas; A. F. Frangi
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Paper Abstract

Gated single photon emission tomography (gSPECT) is a well-established technique used routinely in clinical practice. It can be employed to evaluate global left ventricular (LV) function of a patient. The purpose of this study is to assess LV systolic and diastolic function from gSPECT datasets in comparison with cardiac magnetic resonance imaging (CMR) measurements. This is achieved by applying our recently implemented 3D active shape model (3D-ASM) segmentation approach for gSPECT studies. This methodology allows for generation of 3D LV meshes for all cardiac phases, providing volume time curves and filling rate curves. Both systolic and diastolic functional parameters can be derived from these curves for an assessment of patient condition even at early stages of LV dysfunction. Agreement of functional parameters, with respect to CMR measurements, were analyzed by means of Bland-Altman plots. The analysis included subjects presenting either LV hypertrophy, dilation or myocardial infarction.

Paper Details

Date Published: 27 February 2009
PDF: 8 pages
Proc. SPIE 7262, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, 726227 (27 February 2009); doi: 10.1117/12.813394
Show Author Affiliations
C. Tobon-Gomez, Ctr. for Computational Imaging and Simulation Technologies in Biomedicine, Univ. Pompeu Fabra (Spain)
Networking Ctr. on Biomedical Research (Spain)
CETIR Sant Jordi (Spain)
B. H Bijnens, ICREA (Spain)
Ctr. for Computational Imaging and Simulation Technologies in Biomedicine, Univ. Pompeu Fabra (Spain)
Networking Ctr. on Biomedical Research (Spain)
M. Huguet, CETIR Sant Jordi (Spain)
Networking Ctr. on Biomedical Research (Spain)
F. Sukno, Networking Ctr. on Biomedical Research (Spain)
Ctr. for Computational Imaging and Simulation Technologies in Biomedicine, Univ. Pompeu Fabra (Spain)
G. Moragas, CETIR Unidad Teknon (Spain)
A. F. Frangi, Ctr. for Computational Imaging and Simulation Technologies in Biomedicine, Univ. Pompeu Fabra (Spain)
Networking Ctr. on Biomedical Research (Spain)


Published in SPIE Proceedings Vol. 7262:
Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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