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Proceedings Paper

Destructive fat tissue engineering using photodynamic and selective photothermal effects
Author(s): Valery V. Tuchin; Irina Yu. Yanina; Georgy V. Simonenko
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Paper Abstract

Destructive fat tissue engineering could be realized using the optical method, which provides reduction of regional or site-specific accumulations of subcutaneous adipose tissue on the cell level. We hypothesize that light irradiation due to photodynamic and selective photothermal effects may lead to fat cell lypolytic activity (the enhancement of lipolysis of cell triglycerides due to expression of lipase activity and cell release of free fat acids (FFAs) due to temporal cell membrane porosity), and cell delayed killing due to apoptosis caused by the induced fat cell stress and/or limited cell necrosis.

Paper Details

Date Published: 24 February 2009
PDF: 11 pages
Proc. SPIE 7179, Optics in Tissue Engineering and Regenerative Medicine III, 71790C (24 February 2009); doi: 10.1117/12.812164
Show Author Affiliations
Valery V. Tuchin, Saratov State Univ. (Russian Federation)
Institute of Precise Mechanics and Control (Russian Federation)
Irina Yu. Yanina, Saratov State Univ. (Russian Federation)
Georgy V. Simonenko, Saratov State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 7179:
Optics in Tissue Engineering and Regenerative Medicine III
Sean J. Kirkpatrick; Ruikang Wang, Editor(s)

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