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Proceedings Paper

Three-dimensional heat-induced echo-strain imaging for monitoring high-intensity acoustic ablation
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Paper Abstract

Three dimensional heat-induced echo-strain imaging is a potentially useful tool for monitoring the formation of thermal lesions during ablative therapy. Heat-induced echo-strain, known as thermal strain, is due to the changes in the speed of propagating ultrasound signals and to tissue expansion during heat deposition. This paper presents a complete system for targeting and intraoperative monitoring of thermal ablation by high intensity focused acoustic applicators. A special software interface has been developed to enable motor motion control of 3D mechanical probes and rapid acquisition of 3D-RF data (ultrasound raw data after the beam-forming unit). Ex-vivo phantom and tissue studies were performed in a controlled laboratory environment. While B-mode ultrasound does not clearly identify the development of either necrotic lesions or the deposited thermal dose, the proposed 3D echo-strain imaging can visualize these changes, demonstrating agreement with temperature sensor readings and gross-pathology. Current results also demonstrate feasibility for realtime computation through a parallelized implementation for the algorithm used. Typically, 125 frames per volume can be processed in less than a second. We also demonstrate motion compensation that can account for shift within frames due to either tissue movement or positional error in the US 3D imaging probe.

Paper Details

Date Published: 20 March 2009
PDF: 12 pages
Proc. SPIE 7265, Medical Imaging 2009: Ultrasonic Imaging and Signal Processing, 72650R (20 March 2009); doi: 10.1117/12.811287
Show Author Affiliations
Emad M. Boctor, Johns Hopkins Medical Institutions (United States)
Nishikant Deshmukh, Johns Hopkins Medical Institutions (United States)
Maria S. Ayad, Johns Hopkins Medical Institutions (United States)
Clyde Clarke, Johns Hopkins Medical Institutions (United States)
Kris Dickie, Ultrasonix Medical Corp. (Canada)
Michael A Choti, Johns Hopkins Medical Institutions (United States)
Everette C. Burdette, Acoustic MedSystems, Inc. (United States)

Published in SPIE Proceedings Vol. 7265:
Medical Imaging 2009: Ultrasonic Imaging and Signal Processing
Stephen A. McAleavey; Jan D'hooge, Editor(s)

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