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Proceedings Paper

Detection of non-uniform multi-body motion in image time-series using saccades-enhanced phase correlation
Author(s): Evgeny Gladilin; Roland Eils
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Paper Abstract

Unsupervised analysis of time-series of live-cell images is one of the important tools of quantitative biology. Due to permanent cell motility or displacements of subcellular structures, microscopic images exhibit intrinsic non-uniform motion. In this article, we present a novel approach for detection of non-uniform multi-body motion which is based on combination of the Fourier-phase correlation with iterative probing target and background image regions similar to the strategy known from saccadic eye movements. We derive theoretical expressions that yield plausible explanation why this strategy turns out to be advantageous for tracking particular image pattern. Our experiments with synthetic and live-cell images demonstrate that the proposed approach is capable of accurately detecting non-uniform motion in synthetic and live-cell images.

Paper Details

Date Published: 27 March 2009
PDF: 9 pages
Proc. SPIE 7259, Medical Imaging 2009: Image Processing, 72592D (27 March 2009); doi: 10.1117/12.811120
Show Author Affiliations
Evgeny Gladilin, German Cancer Research Ctr. (Germany)
Roland Eils, German Cancer Research Ctr. (Germany)

Published in SPIE Proceedings Vol. 7259:
Medical Imaging 2009: Image Processing
Josien P. W. Pluim; Benoit M. Dawant, Editor(s)

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