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Proceedings Paper

Mixing characterisation for a serpentine microchannel equipped with embedded barriers
Author(s): K. Khoshmanesh; F. J. Tovar-Lopez; M. Nasabi; A. Z. Kouzani; S. Nahavandi; J. R. Kanwar; S. Baratchi; K. Kalantar-zadeh; A. Mitchell
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Paper Abstract

This paper describes the design, simulation, fabrication and experimental analysis of a passive micromixer for the mixing of biological solvents. The mixer consists of a T-junction, followed by a serpentine microchannel. The serpentine has three arcs, each equipped with circular barriers that are patterned as two opposing triangles. The barriers are engineered to induce periodic perturbations in the flow field and enhance the mixing. CFD (Computational Fluid Dynamics) method is applied to optimise the geometric variables of the mixer before fabrication. The mixer is made from PDMS (Polydimethylsiloxane) using photo- and soft-lithography techniques. Experimental measurements are performed using yellow and blue food dyes as the mixing fluids. The mixing is measured by analysing the composition of the flow's colour across the outlet channel. The performance of the mixer is examined in a wide range of flow rates from 0.5 to 10 μl/min. Mixing efficiencies of higher than 99.4% are obtained in the experiments confirming the results of numerical simulations. The proposed mixer can be employed as a part of lab-on-a-chip for biomedical applications.

Paper Details

Date Published: 30 December 2008
PDF: 11 pages
Proc. SPIE 7270, Biomedical Applications of Micro- and Nanoengineering IV and Complex Systems, 727005 (30 December 2008); doi: 10.1117/12.810678
Show Author Affiliations
K. Khoshmanesh, Deakin Univ. (Australia)
F. J. Tovar-Lopez, RMIT Univ. (Australia)
M. Nasabi, RMIT Univ. (Australia)
A. Z. Kouzani, Deakin Univ. (Australia)
S. Nahavandi, Deakin Univ. (Australia)
J. R. Kanwar, Deakin Univ. (Australia)
S. Baratchi, Deakin Univ. (Australia)
K. Kalantar-zadeh, RMIT Univ. (Australia)
A. Mitchell, RMIT Univ. (Australia)

Published in SPIE Proceedings Vol. 7270:
Biomedical Applications of Micro- and Nanoengineering IV and Complex Systems
Dan V. Nicolau; Guy Metcalfe, Editor(s)

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