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Proceedings Paper

Development of a wireless intra-ocular pressure monitoring system for incorporation into a therapeutic glaucoma drainage implant
Author(s): Tarun Kakaday; Malcolm Plunkett; Steven McInnes; Jim S. Jimmy Li; Nicolas H. Voelcker; Jamie E. Craig
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Paper Abstract

Glaucoma is a common cause of blindness. Wireless, continuous monitoring of intraocular pressure (IOP) is an important, unsolved goal in managing glaucoma. An IOP monitoring system incorporated into a glaucoma drainage implant (GDI) overcomes the design complexity associated with incorporating a similar system in a more confined space within the eye. The device consists of a micro-electro-mechanical systems (MEMS) based capacitive pressure sensor integrated with an inductor printed directly onto a polyimide printed circuit board (PCB). The device is designed to be incorporated onto the external plate of a therapeutic GDI. The resonance frequency changes as a function of IOP, and is tracked remotely using a spectrum analyzer. A theoretical model for the reader antenna was developed to enable maximal inductive coupling with the IOP sensor implant. Pressure chamber tests indicate that the sensor implant has adequate sensitivity in the IOP range with excellent reproducibility over time. Additionally, we show that sensor sensitivity does not change significantly after encapsulation with polydimethylsiloxane (PDMS) to protect the device from fluid environment. In vitro experiments showed that the signal measured wirelessly through sheep corneal and scleral tissue was adequate indicating potential for using the system in human subjects.

Paper Details

Date Published: 30 December 2008
PDF: 11 pages
Proc. SPIE 7270, Biomedical Applications of Micro- and Nanoengineering IV and Complex Systems, 72700O (30 December 2008); doi: 10.1117/12.810647
Show Author Affiliations
Tarun Kakaday, Flinders Univ. (Australia)
Malcolm Plunkett, Ellex Medical Lasers (Australia)
Steven McInnes, Flinders Univ. (Australia)
Jim S. Jimmy Li, Flinders Univ. (Australia)
Nicolas H. Voelcker, Flinders Univ. (Australia)
Jamie E. Craig, Flinders Medical Ctr. (Australia)

Published in SPIE Proceedings Vol. 7270:
Biomedical Applications of Micro- and Nanoengineering IV and Complex Systems
Dan V. Nicolau; Guy Metcalfe, Editor(s)

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