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Proceedings Paper

Functional brain tomography using a time-gated ICCD camera
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Paper Abstract

The mean penetration depth of diffusely reflected photons is dependent on the arrival time t of photons, but not on the source-detector distance. Thus, all photons collected at the same t have the same depth sensitivity, and can be used for the reconstruction. Following this concept, we have implemented a system for 3D tomography using a single injection fiber and a time-gated ICCD camera. The feasibility of the novel approach to reconstruct a local perturbation was demonstrated both with simulations and phantom measurements. Finally, preliminary measurements were performed in vivo following a standard protocol of motor cortex activation.

Paper Details

Date Published: 24 February 2009
PDF: 6 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71741L (24 February 2009); doi: 10.1117/12.809690
Show Author Affiliations
Antonio Pifferi, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Qing Zhao, Istituto Italiano di Tecnologia (Italy)
Lorenzo Spinelli, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Andrea Bassi, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Gianluca Valentini, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Davide Contini, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Rinaldo Cubeddu, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)
Alessandro Torricelli, IIT, ULTRAS–INFM–CNR, and IFN–CNR, Politecnico di Milano (Italy)


Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)

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