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Proceedings Paper

Clinical results with acridine orange using a novel confocal laparoscope
Author(s): Anthony A. Tanbakuchi; Andrew R. Rouse; Kenneth D. Hatch; Arthur F. Gmitro
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Paper Abstract

We previously reported on the development of a multi-spectral confocal laparoscope for clinical imaging. In this paper we present current results using the system to image ovaries with a new laparoscope design using the contrast agent acridine orange. This new laparoscope integrates computer controlled systems for focus, depth scans, and localized contrast agent delivery. Precise axial position control is accomplished with tiny stepper motors integrated inside the laparoscope handle. Ergonomic handle controls allow for data acquisition, deliver of contrast agents, and adjustment of imaging depth during procedures by the surgeon. We have approval to use acridine orange in our clinical trials to image ovaries in vivo during oophorectomies. We present in vivo results using both acridine orange and fluorescein as the topically administered contrast agent.

Paper Details

Date Published: 2 March 2009
PDF: 12 pages
Proc. SPIE 7172, Endoscopic Microscopy IV, 71720H (2 March 2009); doi: 10.1117/12.809540
Show Author Affiliations
Anthony A. Tanbakuchi, College of Optical Sciences, The Univ. of Arizona (United States)
The Univ. of Arizona (United States)
Andrew R. Rouse, The Univ. of Arizona (United States)
Kenneth D. Hatch, The Univ. of Arizona (United States)
Arthur F. Gmitro, College of Optical Sciences, The Univ. of Arizona (United States)
The Univ. of Arizona (United States)


Published in SPIE Proceedings Vol. 7172:
Endoscopic Microscopy IV
Guillermo J. Tearney; Thomas D. Wang, Editor(s)

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