Share Email Print

Proceedings Paper

Development and validation of a system based on spectral-photometry for measuring fluid dynamics of multi-infusion conditions in intensive care units
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Multi-infusion setups for medication administration in Intensive Care Units seem uncontrolled due to flow and pressure differences between syringe pumps. To investigate the dynamics and interaction of multi-infusion, a dedicated set-up was developed to measure the concentrations of fluids dynamically in multiple lines using absorption spectral-photometry. For feasibility testing and calibration, various dyes and concentrations were investigated to find the optimal settings. The developed method was validated and showed satisfactory results for determining mixtures of up to three different dyes in different ratios, with average recoveries of 105.0% (±11.01) for two dyes and 99.6% (±6.26) for three dyes. The method was applied in initial simulation experiments for measuring effects of manipulations in a multi-infusion set-up simulating a clinical situation. Results showed evidence for mutual influencing of separate infusion lines. The method developed for measuring the fluid dynamics of multi-infusion will contribute to a better insight and controlled administration of medications.

Paper Details

Date Published: 23 February 2009
PDF: 8 pages
Proc. SPIE 7170, Design and Quality for Biomedical Technologies II, 71700F (23 February 2009); doi: 10.1117/12.809534
Show Author Affiliations
Annemoon Timmerman, Univ. Medisch Ctr. Utrecht (Netherlands)
Brechtje Riphagen, Univ. Medisch Ctr. Utrecht (Netherlands)
John Klaessens, Univ. Medisch Ctr. Utrecht (Netherlands)
Rudolf Verdaasdonk, Univ. Medisch Ctr. Utrecht (Netherlands)

Published in SPIE Proceedings Vol. 7170:
Design and Quality for Biomedical Technologies II
Ramesh Raghavachari; Rongguang Liang, Editor(s)

© SPIE. Terms of Use
Back to Top