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Proceedings Paper

Simultaneous recovery of chromophore concentrations and ultrasound velocity by spectrally resolved photoacoustic tomography
Author(s): Zhen Yuan; Qizhi Zhang; Stephen Grobmyer; Huabei Jiang
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Paper Abstract

We describe a new spectral approach for inversion of photoacoustic data with multi-wavelength pulsed laser illumination. Multi-spectral PAT provides a means of recovery of different chromophore concentrations and ultrasound velocity simultaneously and directly by incorporating prior spectral information into the image reconstruction process. It is demonstrated from simulation tests and small animal experiments that the multi-parameter recovery based on multispectral PAT is reliable and accurate. The reconstructed multiple parameter images may provide us a key tool to quantify physiological function, disease progression, or response to intervention.

Paper Details

Date Published: 12 February 2009
PDF: 6 pages
Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770Y (12 February 2009); doi: 10.1117/12.809499
Show Author Affiliations
Zhen Yuan, Univ. of Florida (United States)
Qizhi Zhang, Univ. of Florida (United States)
Stephen Grobmyer, Univ. of Florida (United States)
Huabei Jiang, Univ. of Florida (United States)

Published in SPIE Proceedings Vol. 7177:
Photons Plus Ultrasound: Imaging and Sensing 2009
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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