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Proceedings Paper

In vivo bi-directional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities
Author(s): Rene M. Werkmeister; Nikolaus Dragostinoff; Michael Pircher; Erich Götzinger; Christoph K. Hitzenberger; Rainer A. Leitgeb; Leopold Schmetterer
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Paper Abstract

A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.

Paper Details

Date Published: 24 February 2009
PDF: 7 pages
Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71681P (24 February 2009); doi: 10.1117/12.809382
Show Author Affiliations
Rene M. Werkmeister, Medical Univ. of Vienna (Austria)
Nikolaus Dragostinoff, Medical Univ. of Vienna (Austria)
Michael Pircher, Medical Univ. of Vienna (Austria)
Erich Götzinger, Medical Univ. of Vienna (Austria)
Christoph K. Hitzenberger, Medical Univ. of Vienna (Austria)
Rainer A. Leitgeb, Medical Univ. of Vienna (Austria)
Leopold Schmetterer, Medical Univ. of Vienna (Austria)

Published in SPIE Proceedings Vol. 7168:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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