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Proceedings Paper

In-vivo imaging of microcirculation using integrated photoacoustic and optical-coherence microscopy
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Paper Abstract

Photoacoustic imaging and optical coherence tomography have complementary imaging contrasts. Photoacoustic imaging is sensitive to optical absorption, thus is able to generate detailed maps of deep microvasculature in vivo. Optical coherence tomography exploits the optical scattering contrast, and can provide real-time, micrometer-resolution imaging of tissue. We integrate an optical-resolution photoacoustic microscopy and a spectral-domain optical coherence tomography into a single system. Our preliminary experiments showed that it could be a valuable imaging tool for microcirculation studies in vivo.

Paper Details

Date Published: 24 February 2009
PDF: 8 pages
Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770I (24 February 2009); doi: 10.1117/12.809323
Show Author Affiliations
Li Li, Washington Univ. in St. Louis (United States)
Konstantin I. Maslov, Washington Univ. in St. Louis (United States)
Geng Ku, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 7177:
Photons Plus Ultrasound: Imaging and Sensing 2009
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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