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Proceedings Paper

Solid state photomultipliers for biomedical imaging applications
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Paper Abstract

Photomultiplier tubes (PMTs) are often used in scanning imaging systems requiring high sensitivity, due to their low noise and high gain. Solid-state photomultipliers (SSPMs), an array of independent Geiger-mode avalanche photodiodes, each with an integrated quenching resistor, have shown potential to outperform PMTs in terms of signal to noise ratio (SNR) because of higher achievable photon detection efficiency and lower excessive noise factor. Here, the factors affecting SNR of commercially available PMTs and SSPMs will be compared under different wavelengths (simulating dye emissions: 500-700 nm) in order to quantify the potential performance gain when PMTs are replaced by SSPMs.

Paper Details

Date Published: 12 February 2009
PDF: 11 pages
Proc. SPIE 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, 718218 (12 February 2009); doi: 10.1117/12.809264
Show Author Affiliations
Gin-Chung Wang, General Electric Global Research (United States)
Jeffrey Gordon, General Electric Global Research (United States)


Published in SPIE Proceedings Vol. 7182:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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