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Proceedings Paper

Comparative study of laser and lamp fluorescence of cancer and normal tissue through wavelet transform and singular value decomposition
Author(s): Anita H. Gharekhan; Dhaitri Rath; Ashok N. Oza; Asima Pradhan; M. B. Sureshkumar; Prasanta K. Panigrahi
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Paper Abstract

A systematic investigation of the fluorescence characteristics of normal and cancerous human breast tissues is carried out, using laser and lamp as excitation sources. It is found that earlier observed subtle differences between these two tissue types in the wavelet domain are absent, when lamp is used as excitation source. However, singular value decomposition of the average spectral profile in the wavelet domain yields strong correlation for the cancer tissues in the 580-750 nm regimes indicating weak fluorophore activity in this wavelength range.

Paper Details

Date Published: 12 February 2009
PDF: 8 pages
Proc. SPIE 7176, Dynamics and Fluctuations in Biomedical Photonics VI, 717608 (12 February 2009); doi: 10.1117/12.809133
Show Author Affiliations
Anita H. Gharekhan, Gujarat Univ. (India)
Dhaitri Rath, Indian Institute of Technology Kanpur (India)
Ashok N. Oza, Gujarat Univ. (India)
Asima Pradhan, Indian Institute of Technology Kanpur (India)
M. B. Sureshkumar, M.S. Univ. of Baroda (India)
Prasanta K. Panigrahi, Physical Research Lab. (India)
Indian Institute of Science Education and Research, Kolkata (India)

Published in SPIE Proceedings Vol. 7176:
Dynamics and Fluctuations in Biomedical Photonics VI
Valery Viktorovich Tuchin; Lihong V. Wang; Donald D. Duncan, Editor(s)

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