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Proceedings Paper

Ex vivo imaging of human pathologies with integrated optical coherence tomography (OCT) and optical coherence microscopy (OCM)
Author(s): Chao Zhou; Aaron D. Aguirre; Yihong Wang; Bradley Bryan; Tsung-Han Tsai; James L. Connolly; James G. Fujimoto
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Paper Abstract

We report an imaging study using integrated 3D-OCT and OCM for the assessment of various human thyroid and breast pathologies. The 3D-OCT data sets enable en face projection imaging, which provides large field of view with uniform focus and signal level, while OCM provides high magnification that enables cellular resolution imaging. We have demonstrated that the integrated 3D-OCT and OCM technology provide a substantial improvement over standard OCT for the visualization of tissue pathology and can serve as a useful imaging tool in the clinical settings.

Paper Details

Date Published: 20 February 2009
PDF: 8 pages
Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71680N (20 February 2009); doi: 10.1117/12.809064
Show Author Affiliations
Chao Zhou, Massachusetts Institute of Technology (United States)
Aaron D. Aguirre, Massachusetts Institute of Technology (United States)
Harvard-MIT Division of Health Sciences and Technology (United States)
Yihong Wang, Beth Israel Deaconess Medical Ctr. (United States)
Bradley Bryan, Beth Israel Deaconess Medical Ctr. (United States)
Tsung-Han Tsai, Massachusetts Institute of Technology (United States)
James L. Connolly, Beth Israel Deaconess Medical Ctr. (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 7168:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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