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Proceedings Paper

Nanoporous thin film platform for biophotonic sensors
Author(s): Suresh Alla; Rina Solanki; Yvette D. Mattley; Harish Dabhi; Mahmoud R. Shahriari
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Paper Abstract

A Nanoporous glass matrix is developed to encapsulate molecular probes for monitoring important biological parameters such as DO. The hydrophobic nanoporous host matrix is designed and fabricated using room temperature sol gel technique. The doped sol gel is then coated on biocompatible self adhesive patches or directly coated on the biocontainers. We demonstrate the application of this technique in non-invasive monitoring DO as well as oxygen partial pressure in a closed fermentation process as well as in a cell culture plate during bacterial growth. Dynamic response of sensor, sensitivity and accuracy is also demonstrated in this paper.

Paper Details

Date Published: 20 February 2009
PDF: 8 pages
Proc. SPIE 7173, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications IX, 717304 (20 February 2009); doi: 10.1117/12.808994
Show Author Affiliations
Suresh Alla, Ocean Optics, Inc. (United States)
Rina Solanki, Ocean Optics, Inc. (United States)
Yvette D. Mattley, Ocean Optics, Inc. (United States)
Harish Dabhi, Ocean Optics, Inc. (United States)
Mahmoud R. Shahriari, Ocean Optics, Inc. (United States)

Published in SPIE Proceedings Vol. 7173:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications IX
Israel Gannot, Editor(s)

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