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Proceedings Paper

Computational model of retinal photocoagulation and rupture
Author(s): Christopher Sramek; Yannis M. Paulus; Hiroyuki Nomoto; Phil Huie; Daniel Palanker
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Paper Abstract

In patterned scanning laser photocoagulation, shorter duration (< 20 ms) pulses help reduce thermal damage beyond the photoreceptor layer, decrease treatment time and minimize pain. However, safe therapeutic window (defined as the ratio of rupture threshold power to that of light coagulation) decreases for shorter exposures. To quantify the extent of thermal damage in the retina, and maximize the therapeutic window, we developed a computational model of retinal photocoagulation and rupture. Model parameters were adjusted to match measured thresholds of vaporization, coagulation, and retinal pigment epithelial (RPE) damage. Computed lesion width agreed with histological measurements in a wide range of pulse durations and power. Application of ring-shaped beam profile was predicted to double the therapeutic window width for exposures in the range of 1 - 10 ms.

Paper Details

Date Published: 23 February 2009
PDF: 12 pages
Proc. SPIE 7163, Ophthalmic Technologies XIX, 71630T (23 February 2009); doi: 10.1117/12.808556
Show Author Affiliations
Christopher Sramek, Stanford Univ. (United States)
Yannis M. Paulus, Stanford Univ. (United States)
Hiroyuki Nomoto, Stanford Univ. (United States)
Phil Huie, Stanford Univ. (United States)
Daniel Palanker, Stanford Univ. (United States)

Published in SPIE Proceedings Vol. 7163:
Ophthalmic Technologies XIX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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