
Proceedings Paper
Combined Monte Carlo and path-integral method for simulated library of time-resolved reflectance curves from layered tissue modelsFormat | Member Price | Non-Member Price |
---|---|---|
$14.40 | $18.00 |
![]() |
GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. | Check Access |
Paper Abstract
Monte Carlo (MC) simulations are considered the "gold standard" for mathematical description of photon transport in
tissue, but they can require large computation times. Therefore, it is important to develop simple and efficient methods
for accelerating MC simulations, especially when a large "library" of related simulations is needed. A semi-analytical
method involving MC simulations and a path-integral (PI) based scaling technique generated time-resolved reflectance
curves from layered tissue models. First, a zero-absorption MC simulation was run for a tissue model with fixed
scattering properties in each layer. Then, a closed-form expression for the average classical path of a photon in tissue
was used to determine the percentage of time that the photon spent in each layer, to create a weighted Beer-Lambert
factor to scale the time-resolved reflectance of the simulated
zero-absorption tissue model. This method is a unique
alternative to other scaling techniques in that it does not require the path length or number of collisions of each photon to
be stored during the initial simulation. Effects of various layer thicknesses and absorption and scattering coefficients on
the accuracy of the method will be discussed.
Paper Details
Date Published: 25 February 2009
PDF: 9 pages
Proc. SPIE 7175, Optical Interactions with Tissue and Cells XX, 717518 (25 February 2009); doi: 10.1117/12.808423
Published in SPIE Proceedings Vol. 7175:
Optical Interactions with Tissue and Cells XX
Steven L. Jacques; E. Duco Jansen; William P. Roach, Editor(s)
PDF: 9 pages
Proc. SPIE 7175, Optical Interactions with Tissue and Cells XX, 717518 (25 February 2009); doi: 10.1117/12.808423
Show Author Affiliations
Mary-Ann Mycek, Univ. of Michigan (United States)
Published in SPIE Proceedings Vol. 7175:
Optical Interactions with Tissue and Cells XX
Steven L. Jacques; E. Duco Jansen; William P. Roach, Editor(s)
© SPIE. Terms of Use
