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Proceedings Paper

Double layer estimation of flow changes using diffuse correlation spectroscopy
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Paper Abstract

In this work, we explore diffuse correlation spectroscopy (DCS) in a two-layered geometry. We compare the effiency of an homogeneous and a two-layered model to recover flow changes. By simulating a realistic human head with MRI anatomical data, we show that the two-layered model allows distinction between superficial layers and brain hemodynamic changes. The results show that the two-layered model provides a better estimate for the flow change than the homogeneous one. Experimental measurements with a two-layered dynamical phantom confirm the ability of the two-layered analytical model to distinguish flow increase in each layer.

Paper Details

Date Published: 12 February 2009
PDF: 12 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 717407 (12 February 2009); doi: 10.1117/12.808272
Show Author Affiliations
Louis Gagnon, Massachusetts General Hospital (United States)
École Polytechnique de Montréal (Canada)
Univ. de Gériatrie de Montréal (Canada)
Michèle Desjardins, École Polytechnique de Montréal (Canada)
Univ. de Gériatrie de Montréal (Canada)
Louis Bherer, Univ. du Québec à Montréal (Canada)
Frédéric Lesage, École Polytechnique de Montréal (Canada)
Univ. de Gériatrie de Montréal (Canada)


Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)

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