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Proceedings Paper

Optical mammography: improved sensitivity by combined absorption and fluorescence analysis
Author(s): Anaïs Leproux; Marjolein van der Voort; Rik Harbers; Wim Verhaegh; Leon Bakker; Tim Nielsen; Bernhard Brendel; Martin van der Mark
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Paper Abstract

We present a method to enhance tumor detectability in breasts imaged with our optical fluorescence mammography system. During a measurement, transmission data at 4 wavelengths and fluorescence data for excitation at 1 wavelength are collected after injection of an optical contrast agent. The data are reconstructed into 3D images of the absorption and fluorescence distributions. Combining those images enables the identification of various breast tissue compounds. Here, we investigate the relevance of our method in phantom experiments.

Paper Details

Date Published: 12 February 2009
PDF: 12 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740V (12 February 2009); doi: 10.1117/12.808190
Show Author Affiliations
Anaïs Leproux, Philips Research (Netherlands)
Marjolein van der Voort, Philips Research (Netherlands)
Rik Harbers, Philips Research (Netherlands)
Wim Verhaegh, Philips Research (Netherlands)
Leon Bakker, Philips Research (Netherlands)
Tim Nielsen, Philips Research (Germany)
Bernhard Brendel, Philips Research (Germany)
Martin van der Mark, Philips Research (Netherlands)

Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)

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