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Proceedings Paper

Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth
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Paper Abstract

The clinical motivation for our work was to help surgeons see vessels through non-translucent intraoperative tissues during laparoscopic removal of the gallbladder. Our main focus was to answer the question of how CW imaging performs relative to ICCD (Intensified Charge-Coupled Device) based time-gated imaging, which is a lot more costly, under broad Gaussian beam illumination conditions. We have studied the simplified case of an isolated bile duct embedded at different depths within a 2 cm slab of adipose tissue. Monte Carlo simulations were preformed for both reflectance and trans-illumination geometries. The relative performance of CW versus time-gated imaging was compared in terms of spatial resolution and vessel detection sensitivity in the resulting simulated images. Experiments were performed in reflectance geometry to validate simulation results. It was found that time-gated imaging offers superior spatial resolution and vessel detection sensitivity in all cases though CW trans-illumination measurements may also offer satisfactory performance for this tissue geometry at a lower cost.

Paper Details

Date Published: 12 February 2009
PDF: 9 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740B (12 February 2009); doi: 10.1117/12.807887
Show Author Affiliations
George Alexandrakis, Univ. of Texas at Arlington (United States)
Nimit L. Patel, Univ. of Texas at Arlington (United States)
Zi-Jing Lin, Univ. of Texas at Arlington (United States)
Edward H. Livingston, Univ. of Texas Southwestern Medical Ctr. at Dallas (United States)
Hanli Liu, Univ. of Texas at Arlington (United States)


Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)

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