Share Email Print
cover

Proceedings Paper

Fast inverse Monte Carlo simulation for extracting the optical properties of cylindrical tissue
Author(s): Huijuan Zhao; Xiaoqing Zhou; Hao Li; Jierong Ma; Kexin Xu
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

This article aims at the development of the fast inverse Monte Carlo (MC) simulation for the reconstruction of optical properties (absorption coefficient and scattering coefficient ) of cylindrical tissue [1], such as a cervix, from the measurement of near infrared diffuse light on frequency domain. Frequency domain information (amplitude and phase) is extracted from the time domain MC with a modified method. To shorten the computation time in reconstruction of optical properties, efficient and fast forward MC has to be achieved. To do this, firstly, databases of the frequency-domain information under a range of μa and μs were pre-built by combining MC simulation with Lambert-Beer's law. Then, a double polynomial model was adopted to quickly obtain the frequency-domain information in any optical properties. Based on the fast forward MC, the optical properties can be quickly obtained in a nonlinear optimization scheme. Reconstruction resulting from simulated data showed that the developed inverse MC method has the advantages in both the reconstruction accuracy and computation time. The relative errors in reconstruction of the μa and μs are less than ±6% and ±12% respectively, while another coefficient (μa or μs) is in a fixed value. When both μa and μs are unknown, the relative errors in reconstruction of the reduced scattering coefficient and absorption coefficient are mainly less than ±10% in range of 45 < μs <80 cm-1 and 0.25< μa <0.55 cm-1. With the rapid reconstruction strategy developed in this article the computation time for reconstructing one set of the optical properties is less than 0.5 second.

Paper Details

Date Published: 12 February 2009
PDF: 9 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71741P (12 February 2009); doi: 10.1117/12.807580
Show Author Affiliations
Huijuan Zhao, Tianjin Univ. (China)
Xiaoqing Zhou, Tianjin Univ. (China)
Hao Li, Tianjin Univ. (China)
Jierong Ma, Tianjin Univ. (China)
Kexin Xu, Tianjin Univ. (China)


Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)

© SPIE. Terms of Use
Back to Top