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Proceedings Paper

The development of a real-time monitoring and auto-controlling PDT system
Author(s): Jiumin Yang; Yingxin Li; Tiegen Liu; Yu Zhao
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Paper Abstract

Measurement of concentration of photosensitizer, tissue oxygen can reveal information about tissue metabolism and effects of photodynamic therapy (PDT). The purpose of this study is to develop a monitoring and auto-controlling laser system for PDT instrument. The concentration of issue oxygen is detected by near-infrared spectroscopy (NIRS). The blood drug level of photosensitizer is monitored during PDT by fluorescence spectroscopy which was induced by 532 nm Laser. The Laser's output power and idle time can be determined by those monitored parameters. Thus, this system will provide insights into ways to enhance treatment's effectiveness and selectivity in clinical operation.

Paper Details

Date Published: 13 October 2008
PDF: 4 pages
Proc. SPIE 7129, Seventh International Symposium on Instrumentation and Control Technology: Optoelectronic Technology and Instruments, Control Theory and Automation, and Space Exploration, 71291S (13 October 2008); doi: 10.1117/12.807510
Show Author Affiliations
Jiumin Yang, Tianjin Univ. (China)
Tianjin Medical Univ. (China)
Yingxin Li, Tianjin Medical Univ. (China)
Tiegen Liu, Tianjin Univ. (China)
Yu Zhao, Tianjin Medical Univ. (China)


Published in SPIE Proceedings Vol. 7129:
Seventh International Symposium on Instrumentation and Control Technology: Optoelectronic Technology and Instruments, Control Theory and Automation, and Space Exploration

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