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Proceedings Paper

Ultrasound elastography: enabling technology for image guided laparoscopic prostatectomy
Author(s): Ioana N. Fleming; Hassan Rivaz; Katarzyna Macura; Li-Ming Su; Ulrike Hamper; Gwen A Lagoda; Arthur L Burnett; Tamara Lotan; Russell H. Taylor; Gregory D. Hager; Emad M. Boctor
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Paper Abstract

Radical prostatectomy using the laparoscopic and robot-assisted approach lacks tactile feedback. Without palpation, the surgeon needs an affordable imaging technology which can be easily incorporated into the laparoscopic surgical procedure, allowing for precise real time intraoperative tumor localization that will guide the extent of surgical resection. Ultrasound elastography (USE) is a novel ultrasound imaging technology that can detect differences in tissue density or stiffness based on tissue deformation. USE was evaluated here as an enabling technology for image guided laparoscopic prostatectomy. USE using a 2D Dynamic Programming (DP) algorithm was applied on data from ex vivo human prostate specimens. It proved consistent in identification of lesions; hard and soft, malignant and benign, located in the prostate's central gland or in the peripheral zone. We noticed the 2D DP method was able to generate low-noise elastograms using two frames belonging to the same compression or relaxation part of the palpation excitation, even at compression rates up to 10%. Good preliminary results were validated by pathology findings, and also by in vivo and ex vivo MR imaging. We also evaluated the use of ultrasound elastography for imaging cavernous nerves; here we present data from animal model experiments.

Paper Details

Date Published: 13 March 2009
PDF: 12 pages
Proc. SPIE 7261, Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, 72612I (13 March 2009); doi: 10.1117/12.806507
Show Author Affiliations
Ioana N. Fleming, The Johns Hopkins Univ. (United States)
Hassan Rivaz, The Johns Hopkins Univ. (United States)
Katarzyna Macura, Johns Hopkins Medical Institutions (United States)
Li-Ming Su, Univ. of Florida College of Medicine (United States)
Ulrike Hamper, Johns Hopkins Medical Institutions (United States)
Gwen A Lagoda, Johns Hopkins Medical Institutions (United States)
Arthur L Burnett, Johns Hopkins Medical Institutions (United States)
Tamara Lotan, Johns Hopkins Medical Institutions (United States)
Russell H. Taylor, The Johns Hopkins Univ. (United States)
Gregory D. Hager, The Johns Hopkins Univ. (United States)
Emad M. Boctor, Johns Hopkins Medical Institutions (United States)


Published in SPIE Proceedings Vol. 7261:
Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling
Michael I. Miga; Kenneth H. Wong, Editor(s)

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