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Proceedings Paper

Simultaneous wireless electrophysiological and neurochemical monitoring
Author(s): Kartikeya Murari; Mohsen Mollazadeh; Nitish Thakor; Gert Cauwenberghs
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Paper Abstract

Information processing and propagation in the central nervous system is mostly electrical in nature. At synapses, electrical signals cause the release of neurotransmitters like dopamine, glutamate etc., that are sensed by post-synaptic neurons resulting in signal propagation or inhibition. It can be very informative to monitor electrical and neurochemical signals simultaneously to understand the mechanisms underlying normal or abnormal brain function. We present an integrated system for the simultaneous wireless acquisition of neurophysiological and neurochemical activity. Applications of the system to neuroscience include monitoring EEG and glutamate in rat somatosensory cortex following global ischemia.

Paper Details

Date Published: 29 August 2008
PDF: 11 pages
Proc. SPIE 7035, Biosensing, 70350Q (29 August 2008); doi: 10.1117/12.801235
Show Author Affiliations
Kartikeya Murari, Johns Hopkins Univ. School of Medicine (United States)
Mohsen Mollazadeh, Johns Hopkins Univ. School of Medicine (United States)
Nitish Thakor, Johns Hopkins Univ. School of Medicine (United States)
Gert Cauwenberghs, Univ. of California, San Diego (United States)


Published in SPIE Proceedings Vol. 7035:
Biosensing
Manijeh Razeghi; Hooman Mohseni, Editor(s)

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