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Proceedings Paper

Integration of molecular structures in electrode gaps by dielectrophoresis
Author(s): A. Csáki; St. Berg; Ch. Leiterer; R. Kretschmer; A. Wolff; W. Fritzsche
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Paper Abstract

Although functional molecular constructs promise a variety of interesting properties in combination with parallel realization and molecular precision, the utilization requires usually integration into the macroscopic world such as electrodes or other technical environments. Dielectrophoresis (DEP) represents an interesting approach to manipulate and control objects at the nanoscale, and especially to position them at controlled locations in microelectrode arrangements. Over the years this technique was established in our group and is now able to arrange either metal nanoparticles and/or DNA into these gaps in a highly reproducible manner. Microscopic tools were optimized in order to be able to follow single particles/molecules during the process. This ability greatly improves the potential, because now the key parameters can be easily tuned during live imaging of the controlled objects and their behavior. It was possible to realize bridges of nanoparticles as well as of a few stretched DNA molecules on gold microelectrode structures at chip surfaces. Moreover, DNA positioned by DEP in electrode gaps was metallized and the resulting metal nanostructure characterized. Work is in process to combine the various units as well as processes in order to access more complex functionalities.

Paper Details

Date Published: 29 August 2008
PDF: 5 pages
Proc. SPIE 7035, Biosensing, 70350I (29 August 2008); doi: 10.1117/12.794768
Show Author Affiliations
A. Csáki, Institute of Photonic Technology (Germany)
St. Berg, Institute of Photonic Technology (Germany)
Ch. Leiterer, Institute of Photonic Technology (Germany)
R. Kretschmer, Jenaer Biochip Initiative (Germany)
A. Wolff, Institute of Photonic Technology (Germany)
W. Fritzsche, Institute of Photonic Technology (Germany)


Published in SPIE Proceedings Vol. 7035:
Biosensing
Manijeh Razeghi; Hooman Mohseni, Editor(s)

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