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Proceedings Paper

Noninvasive measurement of intracellular viscoelastic properties
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Paper Abstract

We are exploring a biological application of optical tweezers with fluorescence imaging for microrheometry. Measurement of the power spectrum of Brownian motion of a trapped probe particle or vesicle provides information on the viscoelastic properties of the surrounding medium which can change in response to cellular processes or the effect of drugs.

Paper Details

Date Published: 29 August 2008
PDF: 12 pages
Proc. SPIE 7038, Optical Trapping and Optical Micromanipulation V, 70380D (29 August 2008); doi: 10.1117/12.793591
Show Author Affiliations
Martha B. Alvarez-Elizondo, Tecnológico de Monterrey (Mexico)
Susan H. Roelofs, The Univ. of Queensland (Australia)
Frederic A. Meunier, The Univ. of Queensland (Australia)
Norman Heckenberg, The Univ. of Queensland (Australia)
Halina Rubinsztein-Dunlop, The Univ. of Queensland (Australia)

Published in SPIE Proceedings Vol. 7038:
Optical Trapping and Optical Micromanipulation V
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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