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Proceedings Paper

Experimental results of antigliadin antibodies detection using long period fiber grating
Author(s): J. M. Corres; I. R. Matias; J. Goicoechea; F. J. Arregui; D. Viegas; F. M. Araújo; J. L. Santos
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Paper Abstract

In this work a new nano-biofilm is proposed for the detection of celiac disease (CD). A long-period fiber grating (LPFG) is used as a transducer and the surface of the fiber is coated with a precursor layer of SiO2-nanospheres using the electrostatic self-assembly technique (ESA). This layer has been designed in order to create a substrate of high porosity where the gliadins could be deposited. Under the presence of specific antibodies antigliadin antibodies (AGA) the refractive index of the overlay changes giving a detectable shift in the resonance wavelength of the LPFG. Concentrations as low as 5 ppm were detected.

Paper Details

Date Published: 16 May 2008
PDF: 4 pages
Proc. SPIE 7004, 19th International Conference on Optical Fibre Sensors, 700442 (16 May 2008); doi: 10.1117/12.786076
Show Author Affiliations
J. M. Corres, Univ. Pública de Navarra (Spain)
I. R. Matias, Univ. Pública de Navarra (Spain)
J. Goicoechea, Univ. Pública de Navarra (Spain)
F. J. Arregui, Univ. Pública de Navarra (Spain)
D. Viegas, Univ. do Porto (Portugal)
INESC Porto (Portugal)
F. M. Araújo, INESC Porto (Portugal)
J. L. Santos, Univ. do Porto (Portugal)
INESC Porto (Portugal)

Published in SPIE Proceedings Vol. 7004:
19th International Conference on Optical Fibre Sensors
David Sampson; Stephen Collins; Kyunghwan Oh; Ryozo Yamauchi, Editor(s)

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