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Proceedings Paper

Tilted fibre Bragg gratings for the specific detection of biological species
Author(s): Séverine Maguis; Guillaume Laffont; Pierre Ferdinand; Marie-C. Millot; Khémara Kham; Sébastien Péralta
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Paper Abstract

We present a study aimed at developing fibre-optic-based biosensors for the specific detection of biological species. These sensors rely on the combined use of a Tilted short period Fibre Bragg Grating that detects changes in the refractive index of the surrounding solution and of an electrostatic self-assembly technique: self-assembled polyelectrolyte layers and immobilization of the sensor protein on the fibre surface were used for sensor fabrication. We observed changes in the sensor's spectrum induced by specific binding and we imaged fibre surface with atomic force microscopy (AFM). The results show the feasibility of the sensor for various biological or chemical applications.

Paper Details

Date Published: 16 May 2008
PDF: 4 pages
Proc. SPIE 7004, 19th International Conference on Optical Fibre Sensors, 70043X (16 May 2008); doi: 10.1117/12.786044
Show Author Affiliations
Séverine Maguis, CEA, LIST (France)
Guillaume Laffont, CEA, LIST (France)
Pierre Ferdinand, CEA, LIST (France)
Marie-C. Millot, ICMPE, CNRS-Univ. Paris 12 (France)
Khémara Kham, ICMPE, CNRS-Univ. Paris 12 (France)
Sébastien Péralta, Univ. de Cergy Pontoise (France)

Published in SPIE Proceedings Vol. 7004:
19th International Conference on Optical Fibre Sensors
David Sampson; Stephen Collins; Kyunghwan Oh; Ryozo Yamauchi, Editor(s)

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