Share Email Print

Proceedings Paper

A wavefront intersection algorithm for time-of-flight non-contact diffuse optical tomography of fluorescent inclusions in thick turbid media
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

In previous work, we have introduced a numerical constant fraction discrimination (NCFD) technique for processing time-resolved optical signals. It allows to extract, in a stable manner, the arrival time of early photons emitted by a fluorescent inclusion embedded in a scattering medium. We showed experimentally that these arrival times correlate quasi-linearly with inclusion depth. We now exploit this arrival time vs depth relationship for inferring the inclusion position by way of a time of flight algorithm. The algorithm uses the relative arrival times measured at several detector positions around the scattering medium with respect to a reference detector position. The latter is chosen as that detector position for which the arrival time is shortest. Our approach provides accurate inclusion localization, showing the potential of direct time-of-flight fluorescence diffuse optical tomography.

Paper Details

Date Published: 26 October 2007
PDF: 11 pages
Proc. SPIE 6796, Photonics North 2007, 67960T (26 October 2007); doi: 10.1117/12.782808
Show Author Affiliations
Vincent Robichaud, Univ. de Sherbrooke (Canada)
Yves Bérubé-Lauzière, Univ. de Sherbrooke (Canada)

Published in SPIE Proceedings Vol. 6796:
Photonics North 2007
John Armitage, Editor(s)

© SPIE. Terms of Use
Back to Top