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Proceedings Paper

A wavefront intersection algorithm for time-of-flight non-contact diffuse optical tomography of fluorescent inclusions in thick turbid media
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Paper Abstract

In previous work, we have introduced a numerical constant fraction discrimination (NCFD) technique for processing time-resolved optical signals. It allows to extract, in a stable manner, the arrival time of early photons emitted by a fluorescent inclusion embedded in a scattering medium. We showed experimentally that these arrival times correlate quasi-linearly with inclusion depth. We now exploit this arrival time vs depth relationship for inferring the inclusion position by way of a time of flight algorithm. The algorithm uses the relative arrival times measured at several detector positions around the scattering medium with respect to a reference detector position. The latter is chosen as that detector position for which the arrival time is shortest. Our approach provides accurate inclusion localization, showing the potential of direct time-of-flight fluorescence diffuse optical tomography.

Paper Details

Date Published: 26 October 2007
PDF: 11 pages
Proc. SPIE 6796, Photonics North 2007, 67960T (26 October 2007); doi: 10.1117/12.782808
Show Author Affiliations
Vincent Robichaud, Univ. de Sherbrooke (Canada)
Yves Bérubé-Lauzière, Univ. de Sherbrooke (Canada)

Published in SPIE Proceedings Vol. 6796:
Photonics North 2007

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