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Proceedings Paper

Speckle interferometric system to measure ocular microtremor
Author(s): James P. Ryle; Mohammed Al-Kalbani; Niamh Collins; Unnikrishnan Gopinathan; Gerard Boyle; Davis Coakley; John T. Sheridan
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Paper Abstract

Ocular microtremor (OMT) is a biological high frequency (up to 150Hz) low amplitude (25-2500nm peak to peak) involuntary motion of the human eye. Clinical OMT investigations to date have used eye-contacting mechanical piezoelectric probes or piezoelectric strain gauges. Before contact can be made, the eye must first be anaesthetized. In some cases, this eyelid spasms occur making it impossible to measure OMT. Using the contact probe method, the eye motion is mechanically loaded. Results from clinical studies with this method to date have given electrical signal amplitudes from the probe proportional to the displacement, but not the exact displacement information. Recent studies suggest a number of clinical applications for OMT, these include monitoring the depth of anesthesia of a patient in surgery, prediction of outcome in coma, diagnosis of brain stem death. In addition to this, in patients with neurological disorders such as Multiple Sclerosis and Parkinson's disease, abnormal OMT frequency content is present. In this paper, we design a compact non-contact phase modulating optical fiber speckle interferometer to measure eye motions. We simulate OMT motion using a calibrated piezoelectric vibration simulator and compare results produced using a contact method with those using our optical non-contact method.

Paper Details

Date Published: 2 May 2008
PDF: 11 pages
Proc. SPIE 6991, Biophotonics: Photonic Solutions for Better Health Care, 69910H (2 May 2008); doi: 10.1117/12.782260
Show Author Affiliations
James P. Ryle, Univ. College Dublin (Ireland)
Mohammed Al-Kalbani, St. James's Hospital (Ireland)
Niamh Collins, St. James's Hospital (Ireland)
Unnikrishnan Gopinathan, Univ. College Dublin (Ireland)
Univ. Stuttgart (Germany)
Gerard Boyle, St. James's Hospital (Ireland)
Davis Coakley, St. James's Hospital (Ireland)
John T. Sheridan, Univ. College Dublin (Ireland)

Published in SPIE Proceedings Vol. 6991:
Biophotonics: Photonic Solutions for Better Health Care
Jürgen Popp; Wolfgang Drexler; Valery V. Tuchin; Dennis L. Matthews, Editor(s)

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