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Proceedings Paper

A novel nano-photonics biosensor concept for rapid molecular diagnostics
Author(s): Dion J. W. Klunder; Maarten M. J. W. van Herpen; Aleksey Kolesnychenko; Eefje Hornix; Nicoletta Kahya; Ruth de Boer; Henk Stapert
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Paper Abstract

We present a novel nano-photonics biosensor concept that offers an ultra-high surface specificity and excellent suppression of background signals due to the sample fluid on top of the biosensor. In our contribution, we will briefly discuss the operation principle and fabrication of the biosensor, followed by a more detailed discussion on the experimentally determined performance parameters. Recent results on detection of fluorescently labeled molecules in a highly fluorescent background will be shown, and we will give an outlook on real-time detection of bio-molecules such as proteins and nucleic acids.

Paper Details

Date Published: 9 May 2008
PDF: 9 pages
Proc. SPIE 6991, Biophotonics: Photonic Solutions for Better Health Care, 69910P (9 May 2008); doi: 10.1117/12.781340
Show Author Affiliations
Dion J. W. Klunder, Philips Research Europe (Netherlands)
Maarten M. J. W. van Herpen, Philips Research Europe (Netherlands)
Aleksey Kolesnychenko, Philips Research Europe (Netherlands)
Eefje Hornix, Philips Research Europe (Netherlands)
Nicoletta Kahya, Philips Research Europe (Netherlands)
Ruth de Boer, Philips Research Europe (Netherlands)
Henk Stapert, Philips Corporate Technologies (Netherlands)

Published in SPIE Proceedings Vol. 6991:
Biophotonics: Photonic Solutions for Better Health Care
Jürgen Popp; Wolfgang Drexler; Valery V. Tuchin; Dennis L. Matthews, Editor(s)

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