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Proceedings Paper

Integrated dual-slab waveguide interferometer for glucose concentration detection in the physiological range
Author(s): Meng Wang; Sanna Uusitalo; Miia Määttälä; Risto Myllylä; Markku Känsäkoski
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Paper Abstract

This paper presents a label-free optical biosensor based on a Young's interferometer configuration that uses a vertically integrated dual-slab waveguide interferometer as sensing element. In this element, linearly polarized light is coupled into a dual-slab waveguide chip from the input end-face, and the in-coupled zeroth order mode propagates in separated upper and lower waveguides. At the output end-face, the two closely spaced coherent beams diffract out and produce an interference fringe pattern. An evanescent wave field, generated on the surface of the upper waveguide, probes changes in the refractive index of the studied sample, causing a phase shift in the fringe pattern. Compared to a conventional integrated Young's interferometer utilizing a Y-junction as the beam splitter, the dual-slab waveguide Young's interferometer has the advantage of easy fabrication and large tolerance to the input-coupling beam. This paper builds a measurement system to investigate sensor performance using glucose solutions with various concentrations. These glucose concentration measurements are performed within the physiological range of 30mg/dl ~ 500mg/dl. The results indicate that a dual-slab waveguide interferometer yields an average phase resolution of 0.002 rad, which corresponds to an effective refractive index change of 4×10-8 with an interaction path length of 15 mm.

Paper Details

Date Published: 28 April 2008
PDF: 10 pages
Proc. SPIE 7003, Optical Sensors 2008, 70031N (28 April 2008); doi: 10.1117/12.780184
Show Author Affiliations
Meng Wang, Univ. of Oulu (Finland)
Sanna Uusitalo, VTT Technical Research Ctr. of Finland (Finland)
Miia Määttälä, Univ. of Oulu (Finland)
Risto Myllylä, Univ. of Oulu (Finland)
Markku Känsäkoski, VTT Technical Research Ctr. of Finland (Finland)

Published in SPIE Proceedings Vol. 7003:
Optical Sensors 2008
Francis Berghmans; Patrick P. Meyrueis; Thomas P. Pearsall; Anna Grazia Mignani; Antonello Cutolo, Editor(s)

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