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Proceedings Paper

A low-cost linear DC - 35 MHz high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM)
Author(s): Sylvain Gioux; Vida Kianzad; Razvan Ciocan; Hak Soo Choi; Chad Nelson; Jeffrey Thumm; Robert J. Filkins; Stephen J. Lomnes; John V. Frangioni
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Paper Abstract

Near-infrared (NIR) fluorescence has the potential to provide surgeons with real-time intraoperative image-guidance. Increasing the signal-to-background ratio of fluorescent agents involves delivering a controllable excitation fluence rate of proper wavelength and/or using complementary imaging techniques such as FLIM. In this study we describe a low-cost linear driver circuit capable of driving Light Emitting Diodes (LEDs) from DC to 35 MHz, at high power, and which permit fluorescence CW and lifetime measurements. The electronic circuit Gerber files described in this article and the list of components are available online at www.frangionilab.org.

Paper Details

Date Published: 8 February 2008
PDF: 8 pages
Proc. SPIE 6848, Advanced Biomedical and Clinical Diagnostic Systems VI, 684807 (8 February 2008); doi: 10.1117/12.779196
Show Author Affiliations
Sylvain Gioux, Boston Univ. (United States)
Beth Israel Deaconess Medical Ctr. (United States)
Vida Kianzad, Beth Israel Deaconess Medical Ctr. (United States)
Razvan Ciocan, Beth Israel Deaconess Medical Ctr. (United States)
Hak Soo Choi, Beth Israel Deaconess Medical Ctr. (United States)
Chad Nelson, Maxim Integrated Products, Inc. (United States)
Jeffrey Thumm, Duke River Engineering Co. (United States)
Robert J. Filkins, G.E. Global Research (United States)
Stephen J. Lomnes, G.E. Healthcare (United States)
John V. Frangioni, Beth Israel Deaconess Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 6848:
Advanced Biomedical and Clinical Diagnostic Systems VI
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron; Gerald E. Cohn, Editor(s)

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