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Proceedings Paper

Developments of the in-check platform for diagnostic applications
Author(s): Michele Palmieri; Enrico Alessi; Sabrina Conoci; Mauro Marchi; Gaetano Panvini
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Paper Abstract

In-Check is STMicroelectronics proprietary platform for molecular diagnostics. In-Check lays its foundations on the monolithic integration of microelectronics and micromachining technology MEMS, with microfluidic and optical features, bio-chemical surface functionalization and molecular biology. It comprises a core lab-on-chip device, control and reading instrumentation, a complete suite of software modules, and application protocols. Leveraging on such capabilities, In-Check enables fast, highly sensitive and specific, multi-analytical capability of nucleic acid analysis. The platform provides a unique combination of nucleic acid amplification, by polymerase-chain-reaction and target identification and typing by DNA microarray. These integrated biological functionalities together with top quality standard and process control are key features for a platform to be accepted by the highly demanding modern medical diagnostic. This paper describes recent developments of In-Check and some core biological characterizations.

Paper Details

Date Published: 12 February 2008
PDF: 14 pages
Proc. SPIE 6886, Microfluidics, BioMEMS, and Medical Microsystems VI, 688602 (12 February 2008); doi: 10.1117/12.778331
Show Author Affiliations
Michele Palmieri, STMicroelectronics (Italy)
Enrico Alessi, STMicroelectronics (Italy)
Sabrina Conoci, STMicroelectronics (Italy)
Mauro Marchi, STMicroelectronics (Italy)
Gaetano Panvini, STMicroelectronics (Italy)


Published in SPIE Proceedings Vol. 6886:
Microfluidics, BioMEMS, and Medical Microsystems VI
Wanjun Wang; Claude Vauchier, Editor(s)

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