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Proceedings Paper

Frontiers in optical stimulation of neural tissues: past, present, and future
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Paper Abstract

Since lasers were first used in medicine and biomedical related research there have been a variety of documented effects following the irradiation of neural tissues. The first systematic studies to report the direct stimulatory effect of infrared light on neural tissues were performed by researchers at Vanderbilt University in the rat sciatic nerve. These initial studies demonstrated a set of associated advantages of standard stimulation methods, which lead to much excitement and anticipation from the neuroscience community and industry. The inception of this new field included a partnership between industry and academia to foster the development, not only of the applications but also a series of devices to support the research and ultimate commercialization of technology. Currently several institutions are actively utilizing this technique in various applications including in the cochlear and vestibular systems. As more researchers enter the field and new devices are developed we anticipate the number of applications will continue to grow. Some of the next steps will include the establishment of the safety and efficacy data to move this technique to clinical trials and human use.

Paper Details

Date Published: 20 February 2008
PDF: 12 pages
Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 68540B (20 February 2008); doi: 10.1117/12.776988
Show Author Affiliations
Jonathon Wells, Aculight Corp. (United States)
Mark Bendett, Aculight Corp. (United States)
Jim Webb, Aculight Corp. (United States)
Claus Richter, Northwestern Univ. (United States)
Agnella Izzo, Northwestern Univ. (United States)
E. Duco Jansen, Vanderbilt Univ. (United States)
Anita Mahadevan-Jansen, Vanderbilt Univ. (United States)


Published in SPIE Proceedings Vol. 6854:
Optical Interactions with Tissue and Cells XIX
Steven L. Jacques; William P. Roach; Robert J. Thomas, Editor(s)

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