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Proceedings Paper

Segmentation of myocardial perfusion MR sequences with multi-band active appearance models driven by spatial and temporal features
Author(s): N. Baka; J. Milles; E. A. Hendriks; A. Suinesiaputra; M. Jerosch Herold; J. H. C. Reiber; B. P. F. Lelieveldt
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Paper Abstract

This work investigates knowledge driven segmentation of cardiac MR perfusion sequences. We build upon previous work on multi-band AAMs to integrate into the segmentation both spatial priors about myocardial shape as well as temporal priors about characteristic perfusion patterns. Different temporal and spatial features are developed without a strict need for temporal correspondence across the image sequences. We also investigate which combination of spatial and temporal features yields the best segmentation performance. Our evaluation criteria were boundary errors wrt manual segmentations, area overlap, and convergence envelope. From a quantitative evaluation on 19 perfusion studies, we conclude that a combination of the maximum intensity projection feature and gradient orientation map yields the best segmentation performance, with an average point-to-curve error of 0.9-1 pixel wrt manual contours. We also conclude that addition of different temporal features does not necessarily increase performance.

Paper Details

Date Published: 26 March 2008
PDF: 10 pages
Proc. SPIE 6914, Medical Imaging 2008: Image Processing, 691415 (26 March 2008); doi: 10.1117/12.772660
Show Author Affiliations
N. Baka, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)
Erasmus Medical Ctr. (Netherlands)
J. Milles, Leiden Univ. Medical Ctr. (Netherlands)
E. A. Hendriks, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)
A. Suinesiaputra, Leiden Univ. Medical Ctr. (Netherlands)
M. Jerosch Herold, Brigham and Women's Hospital (United States)
J. H. C. Reiber, Leiden Univ. Medical Ctr. (Netherlands)
B. P. F. Lelieveldt, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)

Published in SPIE Proceedings Vol. 6914:
Medical Imaging 2008: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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