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Proceedings Paper

Development of a fully 3D system model in iterative expectation-maximization reconstruction for cone-beam SPECT
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Paper Abstract

In order to improve reconstructed image quality for cone-beam collimator SPECT, we have developed and implemented a fully 3D reconstruction, using an ordered subsets expectation maximization (OSEM) algorithm, along with a volumetric system model - cone-volume system model (CVSM), a modified attenuation compensation, and a 3D depth- and angle-dependent resolution and sensitivity correction. SPECT data were acquired in a 128×128 matrix, in 120 views with a single circular orbit. Two sets of numerical Defrise phantoms were used to simulate CBC SPECT scans, and low noise and scatter-free projection datasets were obtained using the SimSET Monte Carlo package. The reconstructed images, obtained using OSEM with a line-length system model (LLSM) and a 3D Gaussian post-filter, and OSEM with FVSM and a 3D Gaussian post-filter were quantitatively studied. Overall improvement in the image quality has been observed, including better transaxial resolution, higher contrast-to-noise ratio between hot and cold disks, and better accuracy and lower bias in OSEM-CVSM, compared with OSEM-LLSM.

Paper Details

Date Published: 18 March 2008
PDF: 7 pages
Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69132K (18 March 2008); doi: 10.1117/12.772659
Show Author Affiliations
Hongwei Ye, Syracuse Univ. (United States)
Levon Vogelsang, Syracuse Univ. (United States)
David H. Feiglin, SUNY Upstate Medical Univ. (United States)
Edward D. Lipson, Syracuse Univ. (United States)
SUNY Upstate Medical Univ. (United States)
Andrzej Krol, SUNY Upstate Medical Univ. (United States)
Syracuse Univ. (United States)

Published in SPIE Proceedings Vol. 6913:
Medical Imaging 2008: Physics of Medical Imaging
Jiang Hsieh; Ehsan Samei, Editor(s)

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