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Proceedings Paper

Coronary CT angiography: IVUS image fusion for quantitative plaque and stenosis analyses
Author(s): Henk A. Marquering; Jouke Dijkstra; Quentin J. A. Besnehard; Julien P. M. Duthé; Joanne D. Schuijf; Jeroen J. Bax; Johan H. C. Reiber
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Paper Abstract

Rationale and Objective: Due to the limited temporal and spatial resolution, coronary CT angiographic image quality is not optimal for robust and accurate stenosis quantification, and plaque differentiation and quantification. By combining the high-resolution IVUS images with CT images, a detailed representation of the coronary arteries can be provided in the CT images. Methods: The two vessel data sets are matched using three steps. First, vessel segments are matched using anatomical landmarks. Second, the landmarks are aligned in cross-sectional vessel images. Third, the semi-automatically detected IVUS lumen contours are matched to the CTA data, using manual interaction and automatic registration methods. Results: The IVUS-CTA fusion tool facilitates the unique combined view of the high-resolution IVUS segmentation of the outer vessel wall and lumen-intima transitions on the CT images. The cylindrical projection of the CMPR image decreases the analysis time with 50 percent. The automatic registration of the cross-vessel views decreases the analyses time with 85 percent. Conclusions: The fusion of IVUS images and their segmentation results with coronary CT angiographic images provide a detailed view of the lumen and vessel wall of coronary arteries. The automatic fusion tool makes such a registration feasible for the development and validation of analysis tools.

Paper Details

Date Published: 17 March 2008
PDF: 10 pages
Proc. SPIE 6918, Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling, 69181G (17 March 2008); doi: 10.1117/12.772582
Show Author Affiliations
Henk A. Marquering, Leiden Univ. Medical Ctr. (Netherlands)
Jouke Dijkstra, Leiden Univ. Medical Ctr. (Netherlands)
Quentin J. A. Besnehard, Univ. of Poitiers (France)
Julien P. M. Duthé, Univ. of Poitiers (France)
Joanne D. Schuijf, Leiden Univ. Medical Ctr. (Netherlands)
Jeroen J. Bax, Leiden Univ. Medical Ctr. (Netherlands)
Johan H. C. Reiber, Leiden Univ. Medical Ctr. (Netherlands)

Published in SPIE Proceedings Vol. 6918:
Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling
Michael I. Miga; Kevin Robert Cleary, Editor(s)

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