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Proceedings Paper

Feature selection for computer-aided detection: comparing different selection criteria
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Paper Abstract

In this study we investigated different feature selection methods for use in computer-aided mass detection. The data set we used (1357 malignant mass regions and 58444 normal regions) was much larger than used in previous research where feature selection did not directly improve the performance compared to using the entire feature set. We introduced a new performance measure to be used during feature selection, defined as the mean sensitivity in an interval of the free response operating characteristic (FROC) curve computed on a logarithmic scale. This measure is similar to the final validation performance measure we were optimizing. Therefore it was expected to give better results than more general feature selection criteria. We compared the performance of feature sets selected using the mean sensitivity of the FROC curve to sets selected using the Wilks' lambda statistic and investigated the effect of reducing the skewness in the distribution of the feature values before performing feature selection. In the case of Wilks' lambda, we found that reducing skewness had a clear positive effect, yielding performances similar or exceeding performances obtained when the entire feature set was used. Our results indicate that a general measure like Wilks' lambda selects better performing feature sets than the mean sensitivity of the FROC curve.

Paper Details

Date Published: 17 March 2008
PDF: 8 pages
Proc. SPIE 6915, Medical Imaging 2008: Computer-Aided Diagnosis, 691503 (17 March 2008); doi: 10.1117/12.771972
Show Author Affiliations
Rianne Hupse, Radboud Univ. Nijmegen Medical Ctr. (Netherlands)
Nico Karssemeijer, Radboud Univ. Nijmegen Medical Ctr. (Netherlands)

Published in SPIE Proceedings Vol. 6915:
Medical Imaging 2008: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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