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Proceedings Paper

Highly sensitive evanescent wave combination tapered fiber optic fluorosensor for protein detection
Author(s): Vincent Nardone; Rakesh Kapoor
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Paper Abstract

In this paper we are reporting the development of a highly sensitive evanescent wave combination tapered fiber optic fluorosensor. We have demonstrated detection of 5 pM Bovine Serum Albumin (BSA) protein using these fiber optic sensors. The sensor can be easily adopted for detection of other proteins. Six identical probes were prepared and affinity pure Goat anti-BSA antibodies were immobilized on the probe surface. We could detect signal from all the probes kept in 5 pM to 1 nM BSA solution while no signal was detected from the probes kept in 20 nM labeled ESA solution.

Paper Details

Date Published: 5 February 2008
PDF: 6 pages
Proc. SPIE 6852, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VIII, 685203 (5 February 2008); doi: 10.1117/12.771503
Show Author Affiliations
Vincent Nardone, Univ. of Alabama at Birmingham (United States)
Rakesh Kapoor, Univ. of Alabama at Birmingham (United States)


Published in SPIE Proceedings Vol. 6852:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VIII
Israel Gannot, Editor(s)

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