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Proceedings Paper

Analysis of anatomic variability in children with low mathematical skills
Author(s): Zhaoying Han; Lynn Fuchs; Nikki Davis; Christopher J. Cannistraci; Adam W. Anderson; John C. Gore; Benoit M. Dawant
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Paper Abstract

Mathematical difficulty affects approximately 5-9% of the population. Studies on individuals with dyscalculia, a neurologically based math disorder, provide important insight into the neural correlates of mathematical ability. For example, cognitive theories, neuropsychological studies, and functional neuroimaging studies in individuals with dyscalculia suggest that the bilateral parietal lobes and intraparietal sulcus are central to mathematical performance. The purpose of the present study was to investigate morphological differences in a group of third grade children with poor math skills. We compare population averages of children with low math skill (MD) to gender and age matched controls with average math ability. Anatomical data were gathered with high resolution MRI and four different population averaging methods were used to study the effect of the normalization technique on the results. Statistical results based on the deformation fields between the two groups show anatomical differences in the bilateral parietal lobes, right frontal lobe, and left occipital/parietal lobe.

Paper Details

Date Published: 20 March 2008
PDF: 8 pages
Proc. SPIE 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, 69160S (20 March 2008); doi: 10.1117/12.771214
Show Author Affiliations
Zhaoying Han, Vanderbilt Univ. (United States)
Lynn Fuchs, Vanderbilt Univ. (United States)
Nikki Davis, Vanderbilt Univ. (United States)
Christopher J. Cannistraci, Vanderbilt Univ. (United States)
Adam W. Anderson, Vanderbilt Univ. (United States)
John C. Gore, Vanderbilt Univ. (United States)
Benoit M. Dawant, Vanderbilt Univ. (United States)


Published in SPIE Proceedings Vol. 6916:
Medical Imaging 2008: Physiology, Function, and Structure from Medical Images
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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