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Proceedings Paper

A perfusion phantom for quantitative medical imaging
Author(s): Behzad Ebrahimi; Scott D. Swanson; Bobak Mosadegh; Timothy E. Chupp
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Paper Abstract

A perfusion phantom with unique features and a wide variety of applications in MR and other imaging modalities is presented. The phantom is especially suited for tissue perfusion simulation with diffusible and non-diffusible MR tracers. A network of micro-channels in the scale of actual capillaries replicates the blood flow in tissues. Using microfabrication techniques, networks with any desired pattern can be generated. Since the geometry of networks is known, flow rate, delay, dispersion and other fluid parameters can be exactly calculated using finite elements numerical methods. These calculated results can be used to investigate the accuracy of experimental measurements and the precision of mathematical models.

Paper Details

Date Published: 18 March 2008
PDF: 8 pages
Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69130W (18 March 2008); doi: 10.1117/12.770894
Show Author Affiliations
Behzad Ebrahimi, Univ. of Michigan, Ann Arbor (United States)
Scott D. Swanson, Univ. of Michigan, Ann Arbor (United States)
Bobak Mosadegh, Univ. of Michigan, Ann Arbor (United States)
Timothy E. Chupp, Univ. of Michigan, Ann Arbor (United States)

Published in SPIE Proceedings Vol. 6913:
Medical Imaging 2008: Physics of Medical Imaging
Jiang Hsieh; Ehsan Samei, Editor(s)

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