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Proceedings Paper

Web-based computer-aided-diagnosis (CAD) system for bone age assessment (BAA) of children
Author(s): Aifeng Zhang; Joshua Uyeda; Sinchai Tsao; Kevin Ma; Linda A. Vachon; Brent J. Liu; H. K. Huang
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Paper Abstract

Bone age assessment (BAA) of children is a clinical procedure frequently performed in pediatric radiology to evaluate the stage of skeletal maturation based on a left hand and wrist radiograph. The most commonly used standard: Greulich and Pyle (G&P) Hand Atlas was developed 50 years ago and exclusively based on Caucasian population. Moreover, inter- & intra-observer discrepancies using this method create a need of an objective and automatic BAA method. A digital hand atlas (DHA) has been collected with 1,400 hand images of normal children from Asian, African American, Caucasian and Hispanic descends. Based on DHA, a fully automatic, objective computer-aided-diagnosis (CAD) method was developed and it was adapted to specific population. To bring DHA and CAD method to the clinical environment as a useful tool in assisting radiologist to achieve higher accuracy in BAA, a web-based system with direct connection to a clinical site is designed as a novel clinical implementation approach for online and real time BAA. The core of the system, a CAD server receives the image from clinical site, processes it by the CAD method and finally, generates report. A web service publishes the results and radiologists at the clinical site can review it online within minutes. This prototype can be easily extended to multiple clinical sites and will provide the foundation for broader use of the CAD system for BAA.

Paper Details

Date Published: 12 March 2008
PDF: 6 pages
Proc. SPIE 6919, Medical Imaging 2008: PACS and Imaging Informatics, 69190H (12 March 2008); doi: 10.1117/12.770785
Show Author Affiliations
Aifeng Zhang, Univ. of Southern California (United States)
Joshua Uyeda, Univ. of Southern California (United States)
Sinchai Tsao, Univ. of Southern California (United States)
Kevin Ma, Univ. of Southern California (United States)
Linda A. Vachon, Los Angeles County Women's and Children's Hospital (United States)
Brent J. Liu, Univ. of Southern California (United States)
H. K. Huang, Univ. of Southern California (United States)

Published in SPIE Proceedings Vol. 6919:
Medical Imaging 2008: PACS and Imaging Informatics
Katherine P. Andriole; Khan M. Siddiqui, Editor(s)

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