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Proceedings Paper

Cardiac CT artifact mitigation through decomposition-based image reconstruction
Author(s): Zhuangli Liang; Synho Do; W. Clem Karl; Thomas Brady; Homer Pien
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Paper Abstract

A common problem arising in medical imaging is the suppression of undesired image artifacts with the simultaneous preservation of salient clinical information. Often the proposed processing "cure" introduces its own artifacts in other parts of the image that confound reliable diagnosis. A canonical example is the suppression of artifacts from hyperdense objects, such as metal and calcium. In this paper we propose a new decomposition-based approach to the combined image formation and the suppression of localized image artifacts which is motivated by recent results on image inpainting. The approach, which we term Model-Based Algebraic Iteration (MBAI) processing, decomposes an image into a collection of homogeneous components, each of which can be reconstructed in the manner most appropriate to its underlying nature. Because each component is localized, the effects of processing on that component do not contaminate other areas of the image. Our specific motivation is the mitigation of artifacts in cardiac multi-detector computed tomography (MDCT) images. Recently, MDCT has offered the promise of a non-invasive alternative to invasive coronary angiography to evaluate coronary artery disease. An impediment preventing its utilization as a routine clinical replacement for angiography is the presence of image "blooming" artifacts due to the presence vascular calcium. We develop MBAI for the purpose of ameliorating artifacts in cardiac images and thus increase the applicability of MDCT for the evaluation of at-risk patient population. We demonstrate preliminary results in the reduction of the calcium blooming-effect in software simulation, phantom, ex-vivo, and in-vivo MDCT data.

Paper Details

Date Published: 18 March 2008
PDF: 11 pages
Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69131X (18 March 2008); doi: 10.1117/12.770436
Show Author Affiliations
Zhuangli Liang, Boston Univ. (United States)
Synho Do, Massachusetts General Hospital (United States)
W. Clem Karl, Boston Univ. (United States)
Thomas Brady, Massachusetts General Hospital (United States)
Homer Pien, Massachusetts General Hospital (United States)

Published in SPIE Proceedings Vol. 6913:
Medical Imaging 2008: Physics of Medical Imaging
Jiang Hsieh; Ehsan Samei, Editor(s)

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