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Proceedings Paper

Bruise chromophore concentrations over time
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Paper Abstract

During investigations of potential child and elder abuse, clinicians and forensic practitioners are often asked to offer opinions about the age of a bruise. A commonality between existing methods of bruise aging is analysis of bruise color or estimation of chromophore concentration. Relative chromophore concentration is an underlying factor that determines bruise color. We investigate a method of chromophore concentration estimation that can be employed in a handheld imaging spectrometer with a small number of wavelengths. The method, based on absorbance properties defined by Beer-Lambert's law, allows estimation of differential chromophore concentration between bruised and normal skin. Absorption coefficient data for each chromophore are required to make the estimation. Two different sources of this data are used in the analysis- generated using Independent Component Analysis and taken from published values. Differential concentration values over time, generated using both sources, show correlation to published models of bruise color change over time and total chromophore concentration over time.

Paper Details

Date Published: 1 April 2008
PDF: 11 pages
Proc. SPIE 6915, Medical Imaging 2008: Computer-Aided Diagnosis, 69152S (1 April 2008); doi: 10.1117/12.770399
Show Author Affiliations
Mark G. Duckworth, Georgia Institute of Technology (United States)
Jayme J. Caspall, Georgia Institute of Technology (United States)
Rudolph L. Mappus, Georgia Institute of Technology (United States)
Linghua Kong, Georgia Institute of Technology (United States)
Dingrong Yi, Sunnybrook Health Sciences Ctr., Univ. of Toronto (Canada)
Stephen H. Sprigle, Georgia Institute of Technology (United States)


Published in SPIE Proceedings Vol. 6915:
Medical Imaging 2008: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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